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Characterization of the role of Fhit in suppression of DNA damage

The fragile histidine triad protein, Fhit, has a number of reported tumor suppressive functions which include signaling of apoptosis in cancer cells in vitro and in vivo, modulation of the DNA damage response, down-regulation of target oncogene expression, suppression of tumor growth in vivo, and su...

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Detalhes bibliográficos
Main Authors: Saldivar, Joshua C., Bene, Jessica, Hosseini, Seyed Ali, Miuma, Satoshi, Horton, Susan, Heerema, Nyla, Huebner, Kay
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578162/
https://ncbi.nlm.nih.gov/pubmed/23102829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2012.10.003
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