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Nit1 and Fhit tumor suppressor activities are additive
The Fragile Histidine Triad gene (human FHIT, mouse Fhit) has been shown to act as a tumor suppressor gene. Nit1 and Fhit form a fusion protein, encoded by the NitFhit gene in flies and worms, suggesting that mammalian Nit1 and Fhit proteins, which are encoded by genes on different chromosomes in ma...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2762784/ https://ncbi.nlm.nih.gov/pubmed/19479888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22207 |
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