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Nit1 and Fhit tumor suppressor activities are additive

The Fragile Histidine Triad gene (human FHIT, mouse Fhit) has been shown to act as a tumor suppressor gene. Nit1 and Fhit form a fusion protein, encoded by the NitFhit gene in flies and worms, suggesting that mammalian Nit1 and Fhit proteins, which are encoded by genes on different chromosomes in ma...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sun, Jin, Okumura, Hiroshi, Yearsley, Martha, Frankel, Wendy, Fong, Louise Y., Druck, Teresa, Huebner, Kay
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762784/
https://ncbi.nlm.nih.gov/pubmed/19479888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22207
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