Hepatoprotective role of Sestrin2 against chronic ER stress

Upon prolonged endoplasmic reticulum (ER) stress, cells attenuate protein translation to prevent accumulation of unfolded proteins. Here we show that Sestrin2 is critical for this process. Sestrin2 expression is induced by an ER stress-activated transcription factor CCAAT-enhancer-binding protein be...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Park, Hwan-Woo, Park, Haeli, Ro, Seung-Hyun, Jang, Insook, Semple, Ian A., Kim, David N., Kim, Myungjin, Nam, Myeongjin, Zhang, Deqiang, Yin, Lei, Lee, Jun Hee
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074707/
https://ncbi.nlm.nih.gov/pubmed/24947615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5233
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker