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Rab5 activation promotes focal adhesion disassembly, migration and invasiveness in tumor cells
Migration and invasion are essential steps associated with tumor cell metastasis and increasing evidence points towards endosome trafficking being essential in this process. Indeed, the small GTPase Rab5, a crucial regulator of early endosome dynamics, promotes cell migration in vitro and in vivo. P...
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| Huvudupphovsmän: | , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
The Company of Biologists
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4074302/ https://ncbi.nlm.nih.gov/pubmed/23813952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.119727 |
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