Hypoxia promotes Rab5 activation, leading to tumor cell migration, invasion and metastasis

Hypoxia, a common condition of the tumor microenvironment, is associated with poor patient prognosis, tumor cell migration, invasion and metastasis. Recent evidence suggests that hypoxia alters endosome dynamics in tumor cells, leading to augmented cell proliferation and migration and this is partic...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Silva, Patricio, Mendoza, Pablo, Rivas, Solange, Díaz, Jorge, Moraga, Carolina, Quest, Andrew F.G., Torres, Vicente A.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045416/
https://ncbi.nlm.nih.gov/pubmed/27121131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8794
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