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Role of glycosylation in hypoxia-driven cell migration and invasion

Hypoxia, a common condition of the tumor microenvironment, induces changes in the proteome of cancer cells, mainly via HIF-1, a transcription factor conformed by a constitutively expressed β-subunit and an oxygen-regulated α-subunit. In hypoxia, HIF-1α stabilizes, forms the heterodimeric complex wit...

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Detalhes bibliográficos
Publicado no:Cell Adh Migr
Main Authors: Arriagada, Cecilia, Silva, Patricio, Torres, Vicente A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527385/
https://ncbi.nlm.nih.gov/pubmed/30015560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2018.1491234
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