PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex

Defining the role of epigenetic regulators in hematopoiesis has become critically important, as recurrent mutations or aberrant expression of these genes has been identified in both myeloid and lymphoid hematological malignancies. We found that PRMT4, a type I arginine methyltransferase, whose funct...

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書誌詳細
主要な著者: Vu, Ly P., Perna, Fabiana, Wang, Lan, Voza, Francesca, Figueroa, Maria E., Tempst, Paul, Erdjument-Bromage, Hediye, Gao, Rui, Chen, Sisi, Paietta, Elisabeth, Deblasio, Tony, Melnick, Ari, Liu, Yan, Zhao, Xinyang, Nimer, Stephen D.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073674/
https://ncbi.nlm.nih.gov/pubmed/24332853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.11.025
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