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TNFα and SOCS3 regulate IRS-1 to increase retinal endothelial cell apoptosis
Rates of diabetes are reaching epidemic levels. The key problem in both type 1 and type 2 diabetes is dysfunctional insulin signaling, either due to lack of production or due to impaired insulin sensitivity. A key feature of diabetic retinopathy in animal models is degenerate capillary formation. Th...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4073498/ https://ncbi.nlm.nih.gov/pubmed/22266116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2012.01.003 |
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