TNFα Inhibits IGFBP-3 through Activation of p38α and Casein Kinase 2 in Human Retinal Endothelial Cells

We recently reported a reciprocal relationship between tumor necrosis factor alpha (TNFα) and insulin-like receptor growth factor binding protein 3 (IGFBP-3) in whole retina of normal and IGFBP-3 knockout mice. A similar relationship was also observed in cultured retinal endothelial cells (REC). We...

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Bibliographic Details
Main Authors: Zhang, Qiuhua, Soderland, Dylan, Steinle, Jena J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114743/
https://ncbi.nlm.nih.gov/pubmed/25073020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103578
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