IGFBP-3 and TNF-α Regulate Retinal Endothelial Cell Apoptosis

PURPOSE. We hypothesized that loss of insulin-like growth factor binding protein 3 (IGFBP-3) signaling would produce neuronal changes in the retina similar to early diabetes. METHODS. To understand better the role of IGFBP-3 in the retina, IGFBP-3 knockout (KO) mice were evaluated for neuronal, vasc...

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Autors principals: Zhang, Qiuhua, Jiang, Youde, Miller, Matthew J., Peng, Bonnie, Liu, Li, Soderland, Carl, Tang, Jie, Kern, Timothy S., Pintar, John, Steinle, Jena J.
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2013
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741024/
https://ncbi.nlm.nih.gov/pubmed/23868984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12497
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