A carregar...

Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer’s disease

Synapse number is the best indicator of cognitive impairment In Alzheimer’s disease (AD), yet the respective contributions of Aβ and tau, particularly human wild-type tau, to synapse loss remain undefined. Here, we sought to elucidate the Aβ-dependent changes in wild-type human tau that trigger syna...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chabrier, Meredith A., Cheng, David, Castello, Nicholas A., Green, Kim N., LaFerla, Frank M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072239/
https://ncbi.nlm.nih.gov/pubmed/24440055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.01.007
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!