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Multiple Events Lead to Dendritic Spine Loss in Triple Transgenic Alzheimer's Disease Mice
The pathology of Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β (Aβ) peptide, hyperphosphorylated tau protein, neuronal death, and synaptic loss. By means of long-term two-photon in vivo imaging and confocal imaging, we characterized the spatio-temporal pattern of de...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2982845/ https://ncbi.nlm.nih.gov/pubmed/21103384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015477 |
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