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Glucocorticoids Increase Amyloid-β and Tau Pathology in a Mouse Model of Alzheimer’s Disease

Various environmental and genetic factors influence the onset and progression of Alzheimer’s disease (AD). Dysregulation of the hypothalamic–pituitary–adrenal (HPA) axis, which controls circulating levels of glucocorticoid hormones, occurs early in AD, resulting in increased cortisol levels. Disturb...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Green, Kim N., Billings, Lauren M., Roozendaal, Benno, McGaugh, James L., LaFerla, Frank M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675335/
https://ncbi.nlm.nih.gov/pubmed/16943563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2797-06.2006
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