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Glucocorticoids Increase Amyloid-β and Tau Pathology in a Mouse Model of Alzheimer’s Disease

Various environmental and genetic factors influence the onset and progression of Alzheimer’s disease (AD). Dysregulation of the hypothalamic–pituitary–adrenal (HPA) axis, which controls circulating levels of glucocorticoid hormones, occurs early in AD, resulting in increased cortisol levels. Disturb...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Green, Kim N., Billings, Lauren M., Roozendaal, Benno, McGaugh, James L., LaFerla, Frank M.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675335/
https://ncbi.nlm.nih.gov/pubmed/16943563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2797-06.2006
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