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Chronic copper exposure exacerbates both amyloid and tau pathology and selectively dysregulates cdk5 in a mouse model of AD

Excess copper exposure is thought to be linked to the development of Alzheimer disease (AD) neuropathology. However, the mechanism by which copper affects the central nervous system remains unclear. To investigate the effect of chronic copper exposure on both beta-amyloid and tau pathologies, we tre...

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Detalhes bibliográficos
Main Authors: Kitazawa, Masashi, Cheng, David, LaFerla, Frank M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096128/
https://ncbi.nlm.nih.gov/pubmed/19183260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.05901.x
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