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Chronic copper exposure exacerbates both amyloid and tau pathology and selectively dysregulates cdk5 in a mouse model of AD
Excess copper exposure is thought to be linked to the development of Alzheimer disease (AD) neuropathology. However, the mechanism by which copper affects the central nervous system remains unclear. To investigate the effect of chronic copper exposure on both beta-amyloid and tau pathologies, we tre...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4096128/ https://ncbi.nlm.nih.gov/pubmed/19183260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.05901.x |
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