Lipopolysaccharide-Induced Inflammation Exacerbates Tau Pathology by a Cyclin-Dependent Kinase 5-Mediated Pathway in a Transgenic Model of Alzheimer's Disease

Inflammation is a critical component of the pathogenesis of Alzheimer's disease (AD). Although not an initiator of this disorder, inflammation nonetheless plays a pivotal role as a driving force that can modulate the neuropathology. Here, we characterized the time course of microglia activation...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Kitazawa, Masashi, Oddo, Salvatore, Yamasaki, Tritia R., Green, Kim N., LaFerla, Frank M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2005
Materias:
Neurobiology of Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725603/
https://ncbi.nlm.nih.gov/pubmed/16192374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2868-05.2005
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