Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease

The association between nicotinic acetylcholine receptor (nAChR) dysfunction and cognitive decline in Alzheimer's disease (AD) has been widely exploited for its therapeutic potential. The effects of chronic nicotine exposure on Aβ accumulation have been studied in both humans and animal models,...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Oddo, Salvatore, Caccamo, Antonella, Green, Kim N., Liang, Kevin, Tran, Levina, Chen, Yiling, Leslie, Frances M., LaFerla, Frank M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549455/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15705720/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0408500102
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