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Lithium Reduces Tau Phosphorylation but Not Aβ or Working Memory Deficits in a Transgenic Model with Both Plaques and Tangles
Glycogen synthase kinase 3 (GSK-3) is a major kinase implicated in the pathogenesis of Alzheimer’s disease (AD), and reducing its activity may have therapeutic efficacy. Two variants exist, referred to as GSK-3α and GSK-3β. In addition to the latter’s well-described role in the phosphorylation of ta...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Investigative Pathology
2007
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1854961/ https://ncbi.nlm.nih.gov/pubmed/17456772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.061178 |
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