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Changes in dendritic complexity and spine morphology in transgenic mice expressing human wild-type tau

Neurofibrillary tangles (NFTs) are composed of insoluble, hyperphosphorylated aggregates of the microtubule-associated protein tau and are present in various neurodegenerative diseases, including Alzheimer’s disease (AD). To investigate how tau affects neuronal function during NFT formation and subs...

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Autori principali: Dickstein, Dara L., Brautigam, Hannah, Stockton, Steven D., Schmeidler, James, Hof, Patrick R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032082/
https://ncbi.nlm.nih.gov/pubmed/20213269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-010-0245-1
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