Endogenous Amyloid-β is Necessary for Hippocampal Synaptic Plasticity and Memory

OBJECTIVE: The goal of this study was to investigate the role of endogenous amyloid-β peptide (Aβ) in healthy brain. METHODS: Long-term potentiation (LTP), a type of synaptic plasticity that is thought to be associated with learning and memory, was examined through extracellular field recordings fro...

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Autori principali: Puzzo, Daniela, Privitera, Lucia, Fa', Mauro, Staniszewski, Agnieszka, Hashimoto, Gakuji, Aziz, Fahad, Sakurai, Mikako, Ribe, Elena M., Troy, Carol M., Mercken, Marc, Jung, Sonia S., Palmeri, Agostino, Arancio, Ottavio
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071456/
https://ncbi.nlm.nih.gov/pubmed/21472769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22313
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