Tau is not necessary for amyloid-β–induced synaptic and memory impairments

The amyloid hypothesis posits that the amyloid-beta (Aβ) protein precedes and requires microtubule-associated protein tau in a sort of trigger-bullet mechanism leading to Alzheimer’s disease (AD) pathology. This sequence of events has become dogmatic in the AD field and is used to explain clinical t...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Clin Invest
Egile Nagusiak: Puzzo, Daniela, Argyrousi, Elentina K., Staniszewski, Agnieszka, Zhang, Hong, Calcagno, Elisa, Zuccarello, Elisa, Acquarone, Erica, Fa’, Mauro, Li Puma, Domenica D., Grassi, Claudio, D’Adamio, Luciano, Kanaan, Nicholas M., Fraser, Paul E., Arancio, Ottavio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456211/
https://ncbi.nlm.nih.gov/pubmed/32544084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI137040
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