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Role of phosphodiesterase 5 in synaptic plasticity and memory

Phosphodiesterases (PDEs) are enzymes that break down the phosphodiesteric bond of the cyclic nucleotides, cAMP and cGMP, second messengers that regulate many biological processes. PDEs participate in the regulation of signal transduction by means of a fine regulation of cyclic nucleotides so that t...

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Detalles Bibliográficos
Main Authors: Puzzo, Daniela, Sapienza, Salvatore, Arancio, Ottavio, Palmeri, Agostino
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518390/
https://ncbi.nlm.nih.gov/pubmed/18728748
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