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Chemoenzymatic synthesis and structural characterization of 2-O-sulfated glucuronic acid-containing heparan sulfate hexasaccharides

Heparan sulfate and heparin are highly sulfated polysaccharides that consist of a repeating disaccharide unit of glucosamine and glucuronic or iduronic acid. The 2-O-sulfated iduronic acid (IdoA2S) residue is commonly found in heparan sulfate and heparin; however, 2-O-sulfated glucuronic acid (GlcA2...

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Hlavní autoři: Hsieh, Po-Hung, Xu, Yongmei, Keire, David A, Liu, Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070978/
https://ncbi.nlm.nih.gov/pubmed/24770491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwu032
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