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Facile Chemoenzymatic Synthesis of Biotinylated Heparosan Hexasaccharide
A biotinylated heparosan hexasaccharide was synthesized using one-pot multi-enzyme strategy, in situ activation and transfer of N-trifluoroacetylglucosamine (GlcNTFA) to heparin backbone significantly improved the synthetic efficiency. The biotinylated hexasaccharide could serve as a flexible core t...
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| Publicado no: | Org Biomol Chem |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4472006/ https://ncbi.nlm.nih.gov/pubmed/25858766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob00462d |
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