Efficient chemoenzymatic synthesis of novel galacto-N-biose derivatives and their sialylated forms

Galacto-N-biose (GNB) derivatives were efficiently synthesized from galactose derivatives via a one-pot two-enzyme system containing two promiscuous enzymes from Bifidobacterium infantis: a galactokinase (BiGalK) and a D-galactosyl-β1–3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP). Mono-sialyl...

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Foilsithe in:Chem Commun (Camb)
Main Authors: Li, Lei, Liu, Yonghui, Li, Tiehai, Wang, Wenjun, Yu, Zaikuan, Ma, Cheng, Qu, Jingyao, Zhao, Wei, Chen, Xi, Wang, Peng G
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498953/
https://ncbi.nlm.nih.gov/pubmed/26023910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc03746h
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