One-pot multi-enzyme (OPME) chemoenzymatic synthesis of sialyl-Tn-MUC1 and sialyl-T-MUC1 glycopeptides containing natural or non-natural sialic acid()

A series of STn-MUC1 and ST-MUC1 glycopeptides containing naturally occurring and non-natural sialic acids have been chemoenzymatically synthesized from Tn-MUC1 glycopeptide using one-pot multienzyme (OPME) approaches. In situ generation of the sialyltransferase donor cytidine 5′-monophosphate-siali...

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Autori principali: Malekan, Hamed, Fung, Gabriel, Thon, Vireak, Khedri, Zahra, Yu, Hai, Qu, Jingyao, Li, Yanhong, Ding, Li, Lam, Kit S., Chen, Xi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722252/
https://ncbi.nlm.nih.gov/pubmed/23535562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.02.040
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