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Effective one-pot multienzyme (OPME) synthesis of monotreme milk oligosaccharides and other sialosides containing a 4-O-acetyl sialic acid()

A facile one-pot two-enzyme chemoenzymatic approach has been established for gram (Neu4,5Ac(2)α3Lac, 1.33 g) and preparative-scale (Neu4,5Ac(2)α3LNnT) synthesis of monotreme milk oligosaccharides. Other O-acetyl-5-N-acetylneuraminic acid (Neu4,5Ac(2))- or 4-O-acetyl-5-N-glycolylneuraminic acid (Neu4...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Yu, Hai, Zeng, Jie, Li, Yanhong, Thon, Vireak, Shi, Baojun, Chen, Xi
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036589/
https://ncbi.nlm.nih.gov/pubmed/27548611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob01706a
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