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Design and Synthesis of Active Heparan Sulfate-based Probes
A chemoenzymatic approach for synthesizing heparan sulfate oligosaccharides with a reactive diazoacetyl saccharide residue is reported. The resultant oligosaccharides were demonstrated to serve as specific inhibitors for heparan sulfate sulfotransferases, offering a new set of tools to probe the str...
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| Publicat a: | Chem Commun (Camb) |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4502442/ https://ncbi.nlm.nih.gov/pubmed/26066846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc02008e |
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