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Design and Synthesis of Active Heparan Sulfate-based Probes
A chemoenzymatic approach for synthesizing heparan sulfate oligosaccharides with a reactive diazoacetyl saccharide residue is reported. The resultant oligosaccharides were demonstrated to serve as specific inhibitors for heparan sulfate sulfotransferases, offering a new set of tools to probe the str...
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| Publié dans: | Chem Commun (Camb) |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4502442/ https://ncbi.nlm.nih.gov/pubmed/26066846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc02008e |
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