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Heparan Sulfate Separation, Sequencing, and Isomeric Differentiation: Ion Mobility Spectrometry Reveals Specific Iduronic and Glucuronic Acid-Containing Hexasaccharides

We describe the resolution of heparan sulfate (HS) isomers by chromatographic methods and their subsequent differentiation by mass spectrometry (MS), ion mobility, and (1)H-NMR analysis. The two purified hexasaccharide isomers produced nearly identical MS spectra, quantitative disaccharide profiles,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Schenauer, Matthew R., Meissen, John K., Seo, Youjin, Ames, James B., Leary, Julie A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810830/
https://ncbi.nlm.nih.gov/pubmed/19925012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac902186h
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