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Single-Step Selection of Bivalent Aptamers Validated by Comparison with SELEX Using High-Throughput Sequencing

The identification of nucleic acid aptamers would be advanced if they could be obtained after fewer rounds of selection and amplification. In this paper the identification of bivalent aptamers for thrombin by SELEX and single-step selection are compared using next generation sequencing and motif fin...

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Bibliografiska uppgifter
Huvudupphovsmän: Wilson, Robert, Bourne, Christian, Chaudhuri, Roy R., Gregory, Richard, Kenny, John, Cossins, Andrew
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070925/
https://ncbi.nlm.nih.gov/pubmed/24963654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100572
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