Adoptive transfer of MART-1 T cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma

PURPOSE: It has been demonstrated that large numbers of tumor-specific T cells for adoptive cell transfer (ACT) can be manufactured by retroviral genetic engineering of autologous peripheral blood lymphocytes and expanding them over several weeks. In mouse models, this therapy is optimized when admi...

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Bibliografische gegevens
Hoofdauteurs: Chodon, Thinle, Comin-Anduix, Begonya, Chmielowski, Bartosz, Koya, Richard C, Wu, Zhongqi, Auerbach, Martin, Ng, Charles, Avramis, Earl, Seja, Elizabeth, Villanueva, Arturo, McCannel, Tara A., Ishiyama, Akira, Czernin, Johannes, Radu, Caius G., Wang, Xiaoyan, Gjertson, David W., Cochran, Alistair J., Cornetta, Kenneth, Wong, Deborah J.L., Kaplan-lefko, Paula, Hamid, Omid, Samlowski, Wolfram, Cohen, Peter A., Daniels, Gregory A., Mukherji, Bijay, Yang, Lili, Zack, Jerome A., Kohn, Donald B., Heath, James R., Glaspy, John A., Witte, Owen N., Baltimore, David, Economou, James S., Ribas, Antoni
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070853/
https://ncbi.nlm.nih.gov/pubmed/24634374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-3017
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