Multifunctional T-cell Analyses to Study Response and Progression in Adoptive Cell Transfer Immunotherapy

Adoptive cell transfer (ACT) of genetically engineered T cells expressing cancer-specific T-cell receptors (TCR) is a promising cancer treatment. Here, we investigate the in vivo functional activity and dynamics of the transferred cells by analyzing samples from 3 representative patients with melano...

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Main Authors: Ma, Chao, Cheung, Ann F., Chodon, Thinle, Koya, Richard C., Wu, Zhongqi, Ng, Charles, Avramis, Earl, Cochran, Alistair J., Witte, Owen N., Baltimore, David, Chmielowski, Bartosz, Economou, James S., Comin-Anduix, Begonya, Ribas, Antoni, Heath, James R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716460/
https://ncbi.nlm.nih.gov/pubmed/23519018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0383
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