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Effect of the 3- and 4-Methyl Groups on the Opioid Receptor Properties of N-Substituted trans-3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines
[Image: see text] N-substituted trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines (2a,b) are opioid receptor antagonists where the antagonist properties are not due to the type of N-substituent. In order to gain a better understanding of the contribution that the 3- and 4-methyl groups make to the p...
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| Autores principales: | , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4070716/ https://ncbi.nlm.nih.gov/pubmed/24635568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500184j |
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