Free IL-12p40 Monomer is a Polyfunctional Adapter for Generating Novel IL-12-Like Heterodimers Extracellularly

IL-12p40 partners with the p35 and p19 polypeptides to generate the heterodimeric cytokines IL-12 and IL-23 respectively. These cytokines play critical and distinct roles in host defense. The assembly of these heterodimers is thought to take place within the cell, resulting in the secretion of fully...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Abdi, Kaveh, Singh, Nevil J., Spooner, Eric, Kessler, Benedikt M., Radaev, Sergei, Lantz, Larry, Xiao, Tsan Sam, Matzinger, Polly, Sun, Peter D., Ploegh, Hidde L.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070439/
https://ncbi.nlm.nih.gov/pubmed/24821971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400159
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki