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A Polymorphism in the Coding Region of Il12b promotes IL-12p70 and IL-23 Heterodimer Formation

Interleukin (IL)-12 and IL-23 are heterodimeric cytokines involved in the induction of Th1 and Th17 immune responses. Previous work indicated that a region on chromosome 11 encoding the IL-12 p40 subunit regulates strain differences in susceptibility to murine trinitrobenzene sulfonic acid (TNBS)-in...

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Detalhes bibliográficos
Main Authors: Zwiers, Antonie, Fuss, Ivan J., Seegers, Diana, Konijn, Tanja, Garcia-Vallejo, Juan J., Samson, Janneke N., Strober, Warren, Kraal, Georg, Bouma, Gerd
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673698/
https://ncbi.nlm.nih.gov/pubmed/21321105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001330
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