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A Polymorphism in the Coding Region of Il12b promotes IL-12p70 and IL-23 Heterodimer Formation
Interleukin (IL)-12 and IL-23 are heterodimeric cytokines involved in the induction of Th1 and Th17 immune responses. Previous work indicated that a region on chromosome 11 encoding the IL-12 p40 subunit regulates strain differences in susceptibility to murine trinitrobenzene sulfonic acid (TNBS)-in...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3673698/ https://ncbi.nlm.nih.gov/pubmed/21321105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001330 |
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