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Antigen-activated T cells induce IL-12p75 production from Dendritic cells in an IFN-γ-independent manner

The addition of IL-12p75 to naïve CD4(+) T cells promotes their differentiation toward a T(H)1-type cytokine pattern. Dendritic cells stimulated by LPS generate IL-12p75 but only if the environment also contains IFN-γ. Thus, it appears that IFN-γ is needed to start the response that will result in f...

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Autori principali: Abdi, Kaveh, Singh, Nevil J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008555/
https://ncbi.nlm.nih.gov/pubmed/21044125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-3083.2010.02467.x
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