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A subset of dendritic cells induces CD4(+) T cells to produce IFN-γ by an IL-12–independent but CD70-dependent mechanism in vivo
Interferon (IFN)-γ, a cytokine critical for resistance to infection and tumors, is produced by CD4(+) helper T lymphocytes after stimulation by cultured dendritic cells (DCs) that secrete a cofactor, interleukin (IL)-12. We have identified a major IL-12–independent pathway whereby DCs induce IFN-γ–s...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118574/ https://ncbi.nlm.nih.gov/pubmed/17438065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070176 |
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