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IL-18 and IL-12 induce intestinal inflammation and fatty liver in mice in an IFN-γ dependent manner
BACKGROUND—In murine models of inflammatory bowel disease, colonic inflammation is considered to be caused by an aberrant Th1-type immune response. AIM—To investigate if systemic administration of interleukin (IL)-12 and IL-18 to wild-type BALB/c mice induces liver injury and intestinal inflammation...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2000
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1728143/ https://ncbi.nlm.nih.gov/pubmed/11076875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.47.6.779 |
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