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Astragalus membranaceus up-regulate Cosmc expression and reverse IgA dys-glycosylation in IgA nephropathy

BACKGROUND: Decreased Core I β3-Gal-T-specific molecular chaperone (Cosmc) expression induced IgA1 aberrant glycosylation is the main characteristic of IgA nephropathy (IgAN). This study tried to elucidate the effect of Astragalus membranaceus on Cosmc expression and IgA O-glycosylation of periphera...

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Autors principals: Ji, Ling, Chen, XiaoLei, Zhong, Xiang, Li, Zi, Yang, Lichuan, Fan, Junming, Tang, Wanxing, Qin, Wei
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070356/
https://ncbi.nlm.nih.gov/pubmed/24942185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-14-195
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