Astragalus membranaceus up-regulate Cosmc expression and reverse IgA dys-glycosylation in IgA nephropathy

BACKGROUND: Decreased Core I β3-Gal-T-specific molecular chaperone (Cosmc) expression induced IgA1 aberrant glycosylation is the main characteristic of IgA nephropathy (IgAN). This study tried to elucidate the effect of Astragalus membranaceus on Cosmc expression and IgA O-glycosylation of periphera...

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Autori principali: Ji, Ling, Chen, XiaoLei, Zhong, Xiang, Li, Zi, Yang, Lichuan, Fan, Junming, Tang, Wanxing, Qin, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070356/
https://ncbi.nlm.nih.gov/pubmed/24942185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-14-195
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