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Astragalus membranaceus up-regulate Cosmc expression and reverse IgA dys-glycosylation in IgA nephropathy

BACKGROUND: Decreased Core I β3-Gal-T-specific molecular chaperone (Cosmc) expression induced IgA1 aberrant glycosylation is the main characteristic of IgA nephropathy (IgAN). This study tried to elucidate the effect of Astragalus membranaceus on Cosmc expression and IgA O-glycosylation of periphera...

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Detalhes bibliográficos
Main Authors: Ji, Ling, Chen, XiaoLei, Zhong, Xiang, Li, Zi, Yang, Lichuan, Fan, Junming, Tang, Wanxing, Qin, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070356/
https://ncbi.nlm.nih.gov/pubmed/24942185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-14-195
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