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DNA Methylation in Cosmc Promoter Region and Aberrantly Glycosylated IgA1 Associated with Pediatric IgA Nephropathy

IgA nephropathy (IgAN) is one of the most common glomerular diseases leading to end-stage renal failure. Elevation of aberrantly glycosylated IgA1 is a key feature of it. The expression of the specific molecular chaperone of core1ß1, 3galactosyl transferase (Cosmc) is known to be reduced in IgAN. We...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sun, Qiang, Zhang, Jianqian, Zhou, Nan, Liu, Xiaorong, Shen, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315396/
https://ncbi.nlm.nih.gov/pubmed/25647400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112305
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