Amyloids of Alpha-Synuclein Affect the Structure and Dynamics of Supported Lipid Bilayers

Interactions of monomeric alpha-synuclein (αS) with lipid membranes have been suggested to play an important role in initiating aggregation of αS. We have systematically analyzed the distribution and self-assembly of monomeric αS on supported lipid bilayers. We observe that at protein/lipid ratios h...

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Main Authors: Iyer, Aditya, Petersen, Nils O., Claessens, Mireille M.A.E., Subramaniam, Vinod
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2014
Teme:
Membranes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070068/
https://ncbi.nlm.nih.gov/pubmed/24940776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.05.001
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