Cross-seeding of alpha-synuclein aggregation by amyloid fibrils of food proteins

The aggregation of the protein α-synuclein (aSyn) into amyloid fibrils in the human brain is associated with the development of several neurodegenerative diseases, including Parkinson's disease. The previously observed prion-like spreading of aSyn aggregation throughout the brain and the findin...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Vaneyck, Jonathan, Segers-Nolten, Ine, Broersen, Kerensa, Claessens, Mireille M.A. E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949133/
https://ncbi.nlm.nih.gov/pubmed/33539920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100358
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