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Clustering of α-Synuclein on Supported Lipid Bilayers: Role of Anionic Lipid, Protein, and Divalent Ion Concentration

α-Synuclein is the major component of Lewy body inclusions found in the brains of patients with Parkinson's disease. Several studies indicate that α-synuclein binds to negatively charged phospholipid bilayers. We examined the binding of α-synuclein to membranes containing different amounts of n...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pandey, Anjan P., Haque, Farzin, Rochet, Jean-Christophe, Hovis, Jennifer S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716450/
https://ncbi.nlm.nih.gov/pubmed/19167303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.10.011
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