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Adsorption of α-Synuclein on Lipid Bilayers: Modulating the Structure and Stability of Protein Assemblies

The interaction of α-synuclein with phospholipid membranes has been examined using supported lipid bilayers and epi-fluorescence microscopy. The membranes contained phosphatidylcholine (PC) and phosphatidic acid (PA), which mix at physiological pH. Upon protein adsorption the lipids undergo fluid-fl...

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Detalhes bibliográficos
Main Authors: Haque, Farzin, Pandey, Anjan P., Cambrea, Lee R., Rochet, Jean-Christophe, Hovis, Jennifer S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855901/
https://ncbi.nlm.nih.gov/pubmed/20187615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp1006704
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