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α-Synuclein-Induced Tubule Formation in Lipid Bilayers

α-Synuclein is a presynaptic protein that binds to phospholipid membranes and is involved in the pathogenesis of Parkinson's disease (PD). In this paper we describe the effects of adding wild-type α-synuclein (WT) and three familial PD mutants (A53T, A30P and E46K) to membranes containing 15–35...

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Autori principali: Pandey, Anjan P., Haque, Farzin, Rochet, Jean-Christophe, Hovis, Jennifer S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098118/
https://ncbi.nlm.nih.gov/pubmed/21520980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp1121917
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