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Cyclic Amplification of Prion Protein Misfolding
Protein Misfolfing Cyclic amplification (PMCA) is a technique that take advantage of the nucleation-dependent prion replication process to accelerate the conversion of PrP(C) into PrP(Sc) in the test tube. PMCA uses ultrasound waves to fragment the PrP(Sc) polymers, increasing the amount of seeds pr...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4068802/ https://ncbi.nlm.nih.gov/pubmed/22528092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-551-0_14 |
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