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Limited Activity of Clofazimine as a Single Drug in a Mouse Model of Tuberculosis Exhibiting Caseous Necrotic Granulomas

New drugs and drugs with a novel mechanism of action are desperately needed to shorten the duration of tuberculosis treatment, to prevent the emergence of drug resistance, and to treat multiple-drug-resistant strains of Mycobacterium tuberculosis. Recently, there has been renewed interest in clofazi...

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Autors principals: Irwin, Scott M., Gruppo, Veronica, Brooks, Elizabeth, Gilliland, Janet, Scherman, Michael, Reichlen, Matthew J., Leistikow, Rachel, Kramnik, Igor, Nuermberger, Eric L., Voskuil, Martin I., Lenaerts, Anne J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068578/
https://ncbi.nlm.nih.gov/pubmed/24798275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02565-14
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