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T-bet is essential for Th1-mediated, but not Th17-mediated, CNS autoimmune disease
T cells that produce both IL-17 and IFN-γ, and co-express ROR-γt and T-bet, are often found at sites of autoimmune inflammation. However, it is unknown whether this co-expression of T-bet with ROR-γt is a prerequisite for immunopathology. We show here that T-bet is not required for the development o...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BlackWell Publishing Ltd
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4068221/ https://ncbi.nlm.nih.gov/pubmed/23878019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201343689 |
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